SRF 2024 | Programme

Welcome to the University of Oxford Scientific Research Facilities Conference. Below you'll find the full programme for the day, including key speakers, sessions, and networking opportunities. Please use the information to plan your day.

Day 1: Thursday 26th September

Day One Breaks

10:30

10:50

Coffee break and networking

12:25

13:30

Lunch, networking and poster sessions

15:10

15:30

Coffee break and networking

 

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Session Speaker(s) Talk Title Talk Highlights
(08:30-09:00) Registration Opens      
Welcome Dr Michalina Mazurczyk    
Keynote Speaker Dr Peter O'Toole, Head of Imaging and Cytometry, University of York Evolution/Revolution of Facilities  
Electron Microscopy Session Dr Neil Young, David Cockayne Centre for Electron Microscopy, University of Oxford Electron Microscopy at the DCCEM and ePSIC Introduction to EM and FIB Facilities in central Oxford. The ePSIC facility at Diamond. Overview of expertise and research outputs.
  Dr Helen Duyvesteyn, Oxford Particle Imaging Centre (OPIC) The Oxford Particle Imaging Centre for Cryo-Electron Microscopy
  • Presentation of the cryo-Electron Microscopy facility supporting single particle, FIB-milling, cryo-CLEM, and in-situ tomography, including live pathogen imaging.
  • Instruments include FIB-SEMs for milling/correlative experiments, TEMs for high-resolution single particle/tomography data collection, and ancillary equipment for grid preparation.
  Ms Raman Dhaliwal, Dunn School Electron Microscopy Facility, University of Oxford Electron Microscopy at the Dunn School; Equipment and Capabilities Overview of equipment and capabilities at the Dunn School Electron Microscopy facility.
Q&A      
Coffee Break and Networking
Light Microscopy Session Dr Niloufer Irani, Micron Bioimaging Facility, University of Oxford Imaging at Micron Who we are and how to access, our technology, and Leica Centre of Excellence
  Dr Jana Koth, Wolfson Imaging Centre, University of Oxford Advanced Light Microscopy options at the Wolfson Imaging Centre at the JR hospital campus
  • Available Instruments
  • Work and collaboration Philosophy
  • Unique Capabilities
  Dr James Bancroft, Cellular Imaging Core Facility, University of Oxford Advanced microscopy and analysis with the Cellular Imaging Core Facility
  • Introduction to the facility and workflows
  • Available technologies
  • Example projects
  Dr Helena Coker, Oxford-ZEISS Centre of Excellence in Biomedical Imaging, University of Oxford Advanced microscopy; instrument development and applications opportunities on Old Road The KIR and IDRM shared microscopy facilities, including the Oxford-ZEISS CoE, house advanced microscopes, including some that are rare or unique in Oxford. We have expertise in advanced applications and, as microscope builders, we can adapt
homebuilt systems to specific needs. We are looking for collaborations.
  Dr Alan Wainman, Dunn School Light Microscopy Facility, University of Oxford Imaging in the Dunn School Light Microscopy Facility Overview of light microscopy imaging at Dunn School
  Mr Carl Lee, Digital Pathology Omics Core Facility, The Kennedy Institute, University of Oxford Digital Pathology Omics Core Facility - Multiplex Imaging Overview of multiplex imaging capabilities at the Digital Pathology Omics Core facility.
  Dr Marjorie Fournier, Advanced Proteomics Facility, University of Oxford Proteomics in Life Sciences in Central Oxford
  • Proteomics introduction
  • APF applications
  • Contact details
Q&A      
Lunch, Networking, and Poster Sessions
Session Speaker(s) Talk Title Talk Highlights
Histology Session Dr Ida Parisi, Histology Facility, Kennedy Institute of Rheumatology, NDORMS, MSD Kennedy Institute Histology Facility: scientific support and beyond
  • Description of the histology services provided and the different expertise within the team
  • Description of the equipment in the histology lab
  • Scientific support, public and patient involvement, and engagement
  Dr Alistair Easton, The Translational Histopathology Laboratory, Oxford Cancer, Department of Oncology, MSD The Translational Histopathology Lab Overview of the services and capabilities of the Translational Histopathology Laboratory
Q&A      
Flow and Mass Cytometry Session Mr Jonathan Webber, Flow Cytometry Facility, Kennedy Institute, NDORMS, MSD Flow Cytometry at the KIR Equipment + capabilities, size and capacity, moving into spectral flow
  Dr Craig Waugh, WIMM Flow Cytometry Facility, Weatherall Institute of Molecular Medicine, RDM, MSD Flow cytometry resources at the Weatherall Institute of Molecular Medicine
  • An overview of flow cytometry resources at the WIMM
  • Introduction of the BD FACSDiscover S8 spectral cell sorter with imaging capability
  Dr Robert Hedley, The Don Mason Facility of Flow Cytometry, Sir William Dunn School of Pathology, MSD, University of Oxford See What You Flow at the Don Mason Facility of Flow Cytometry The Don Mason Facility offers both cell analysis and cell sorting services. All cytometers come with optically identical duplicates to offer redundancy in case of breakdown. Make use of the ImageStream imaging cytometer to troubleshoot difficult experiments and see what you are flowing in real-time.
  Ms Michalina Mazurczyk, MRC WIMM Mass Cytometry Facility, MRC Weatherall Institute of Molecular Medicine, RDM, MSD Phenotyping, cell function, metabolism
  • Flow and imaging cytometry by Time-Of-Flight (TOF)
  • Most efficient applications of Flow and Imaging cytometry by TOF for big and small studies
  • Single-cell metabolomics by CyTOF
  Dr David Ahern, Kennedy Institute Mass Cytometry and Imaging SRF, Kennedy Institute of Rheumatology, NDORMS, MSD High-dimensional phenotypic and functional analysis using Mass Cytometry
  • Introduction to mass cytometry
  • Use of mass cytometry for phenotypic analysis of single cells
  • Use of mass cytometry for high-dimensional imaging
Q&A      
Coffee Break and Networking
Mass Spectrometry Session Dr Rod Chalk, Oxford HiSpec Mass Spectrometry Facility, Centre for Medicines Discovery (CMD), NDM, MSD Comprehensive Structural and Functional Analysis of Proteins using Mass Spectrometry
  • OHS is uniquely experienced in top-down, bottom-up, and native mass spectrometry, offering complete structural and functional analysis of any protein
  • Specialisation in “difficult” proteins, including membrane proteins, glycoproteins, protein-protein complexes, and ADCs
  • Accessible, affordable, and fast mass spectrometry, allowing integration into benchtop workflows
  Mr Philip Holdship, ICP-MS Trace Element Analysis, Department of Earth Sciences, MPLS Division, University of Oxford Trace Element Analysis and Single Cell Metallomics/ Single Particle ICP-MS at Earth Sciences
  • Overview of ICP-MS
  • What ICP-MS can measure
  • Single cell/single particle research at Earth Sciences
  Dr Chris Babbs, Genome Engineering and Transgenics, WIMM, RDM/NDCLS, MSD, University of Oxford Overview of Services
  • Service offerings
  • Examples of use in Genome Engineering and Transgenics
Q&A      
Final Remarks Dr Michalina Mazurczyk    

Day 2: Friday 27th September

Day Two Breaks

10:45

10:55

Coffee break and networking

12:55

13:55

Lunch, networking and poster sessions

14:45

15:05

Coffee break and networking

 

Expand All

Session Speaker(s) Talk Title Talk Highlights
(08:30-09:00) Registration Opens      
Welcome      
Single Cell and Genomics Session Dr Paolo Piazza, Technology Platforms, Centre for Human Genetics, Nuffield Department of Medicine (NDM), MSD From NGS Expertise to Cutting-Edge Omics Support
  • Multiomics capabilities
  • Towards a one-stop shop solution for genomics and omics support
  Dr Maria Greco, WIMM Advanced Single Cell Omics Facility, WIMM, RDM, MSD Single Cell Omics and Spatial Transcriptomics - From Service to Training Program
  Dr Timothy Roston, WIMM Sequencing Facility, WIMM, RDM, MSD Sequencing and HLA typing Facility
  Miss Helene Dreau, Oxford Molecular Diagnostic Centre (OMDC), Department of Oncology, MSD OMDC - Supporting Molecular Pathology Testing
  • Sample pre-processing
  • Next-Generation Sequencing (NGS)
  • Bioinformatics support
  Dr Joey Riepsaame, Genome Engineering Oxford, Sir William Dunn School of Pathology, University of Oxford, MSD CRISPR Precision Gene Editing and Library Screening Services at GEO Overview of CRISPR gene editing and library screening services at Genome Engineering Oxford
  Dr Daniel Ebner, Cellular High Throughput Screening, Centre for Medicines Discovery (CMD), NDM, MSD Phenotypic Screening for Drug-Target Discovery - Centre for Medicines Discovery
  • Chemogenomic Drug Target Discovery
  • Functional Genomic Drug Target Discovery
  • Small Molecule/Array Screening and Phenotypic Screening
  Dr Claire Powers, Viral Vector Core Facility (VVCF), Pandemic Science Institute, NDM, MSD The Viral Vector Core Facility (VVCF)
  • Overview of the VVCF
  • Adenoviral vectors
  • Modified Vaccinia Ankara (MVA) vectors
Q&A      
Coffee Break and Networking
Data Storage and Computing Session Mr Kinson Chan, WIMM CCB HPC, WIMM, RDM, MSD HPC Services for Biomedical Sciences Overview of High-Performance Computing services for biomedical research
  Mr Tamas Szommer, Research Informatics Facility, CMD, NDM, MSD Research Informatics Facility Capabilities and notable achievements in research informatics
  Mr Charles Roberts, Biomedical Research Computing (BMRC), Centre for Human Genetics, NDM, MSD Biomedical Research Computing (BMRC)
  • Unified platform suitable for the security and governance requirements of biomedical research computing
  • Cluster compute services, including GPU hardware suitable for AI/ML work
  • On-premises cloud computing and large, fast storage systems
  • Support for troubleshooting, performance tuning, and data transfer challenges
Q&A      
Proteomics and Lipidomics Session Dr Eleanor Williams, Protein Production SRF, CMD, NDM, MSD Bespoke Protein Production and Target Enablement
  • Cloning/Expression/purification facilities available
  • Bespoke approach to working on difficult targets
  • Equipment and training available for university researchers
  Dr Iolanda Vendrell, Discovery Proteomics Facility (DisPro), TDI/CMD, NDM, MSD Application for Bottom-Up Proteomics Using State-of-the-Art LC-MS/MS Platforms Overview of bottom-up proteomics applications using LC-MS/MS technology
  Dr Darragh O'Brien, Structural & Mechanistic Proteomics, CMD, NDM, MSD Using Hydrogen Deuterium Exchange Mass Spectrometry (HDX-MS) to Capture Proteins in Motion
  • HDX-MS as a powerful biophysical tool to gain insights into protein structure and function
  • Characterising protein-ligand interactions, including small molecules, peptides, and other proteins
  • Recent advancements in HDX-MS for drug discovery and design
  Miss Hannah Scott, Metabolomics, Target Discovery Institute, NDM, MSD Lipidomics Research Introduction to the facility and examples of lipidomics applications
Q&A      
Lunch, Networking, and Poster Sessions
Session Speaker(s) Talk Title Talk Highlights
Atomic Interactions Session Ms Rizwana Rashid, Pharmacology Odyssey M Imaging Facility, Pharmacology, MSD, University of Oxford Odyssey M Imaging System from LiCOR Biosciences Overview of the Odyssey M Imaging System and its capabilities in imaging and biosciences
  Dr Mikhail Kutuzov, SPR Facility, Sir William Dunn School of Pathology, MSD, University of Oxford Surface Plasmon Resonance (SPR): A Label-Free Method to Measure Intermolecular Interactions in Real-Time
  • Label-free method with minimal material requirements
  • Works for a wide range of affinities
  • Produces both affinity and kinetic data in real-time (pM to mM)
  Dr David Chivall, Oxford Radiocarbon Accelerator Unit, School of Archaeology, Social Sciences Division Research Laboratory for Archaeology - Isotope Facilities  
Q&A      
Coffee Break and Networking
Clinical and Translational Labs Session Dr Adam Ritchie, Bioprocess & Analytical Development (BiPAD), Jenner Institute, NDM, MSD Translating Medicines from the Lab to the Bedside
  • Preparing products for GMP-compliant medicine manufacturing
  • Development and support for analytics in research or medical manufacturing
  Miss Joana Silva, Therapy Acceleration Laboratory, MRC-WIMM, RDM, MSD Therapy Acceleration Laboratory - What We Offer
  • A team of highly skilled scientists from both NHS and research backgrounds
  • Providing a range of assays in NGS, flow cytometry, and biobanking
  • Quality-led service working to regulations and standards set by HTA, UKAS, and GCLP
  Dr Ryan Beveridge, Clinical Biomanufacturing Facility, Pandemic Sciences Institute, NDM, MSD Bridging the Valley of Death
  • Mission statement of the CBF
  • Explanation of GMP and the structure of the facility
  • Technical abilities of the CBF and planned expansions
  Dr Harold Mackenzie, Chemistry Department NMR Research Facility, Chemistry, MSD, University of Oxford Nuclear Magnetic Resonance (NMR) Spectroscopy in the Department of Chemistry Overview of NMR spectroscopy capabilities and research
  Dr Sebastian Rieger, Neuroimaging Facility, Wellcome Centre for Integrative Neuroimaging, Department of Psychiatry, MSD MRI Facilities at the Wellcome Centre for Integrative Neuroimaging Overview of the MRI facilities and research in neuroimaging
Q&A      
End of Conference Remarks Dr Michalina Mazurczyk